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http://hdl.handle.net/1893/30157| Appears in Collections: | Faculty of Health Sciences and Sport Journal Articles |
| Peer Review Status: | Refereed |
| Title: | A statistical and biological response to an informatics appraisal of healthy aging gene signatures |
| Author(s): | Timmons, James A Gallagher, Iain J Sood, Sanjana Phillips, Bethan Crossland, Hannah Howard, Robert Kraus, William E Atherton, Philip J |
| Issue Date: | 2-Aug-2019 |
| Date Deposited: | 20-Sep-2019 |
| Citation: | Timmons JA, Gallagher IJ, Sood S, Phillips B, Crossland H, Howard R, Kraus WE & Atherton PJ (2019) A statistical and biological response to an informatics appraisal of healthy aging gene signatures. Genome Biology, 20 (1), Art. No.: 152. https://doi.org/10.1186/s13059-019-1734-z |
| Abstract: | Jacob and Speed did not identify even a single example of a ‘150-gene-set’ that was statistically significant at classifying Alzheimer’s disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings. |
| DOI Link: | 10.1186/s13059-019-1734-z |
| Rights: | © 2019 BioMed Central Ltd unless otherwise stated. Part of Springer Nature. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| Licence URL(s): | http://creativecommons.org/licenses/by/4.0/ |
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|---|---|---|---|---|
| s13059-019-1734-z.pdf | Fulltext - Published Version | 717.68 kB | Adobe PDF | View/Open |
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