Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/34022
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dc.contributor.authorHoward, C Vyvyanen_UK
dc.contributor.authorJohnson, David Wen_UK
dc.contributor.authorMorton, Johnen_UK
dc.contributor.authorMichaelis, Susanen_UK
dc.contributor.authorSupplee, Daviden_UK
dc.contributor.authorBurdon, Jonathanen_UK
dc.date.accessioned2022-03-08T01:10:56Z-
dc.date.available2022-03-08T01:10:56Z-
dc.date.issued2018-02en_UK
dc.identifier.urihttp://hdl.handle.net/1893/34022-
dc.description.abstractWe present strong evidence for the presence of aerosols of Nano-particles (also termed Ultrafine Particles (UFPs) in aerosol science) in the breathing air of commercial aircraft using engine bleed air architecture. The physical and chemical nature of engine oils and the high temperatures attained in aircraft jet engines (up to 1700°C in the oil circulation and up to 30,000°C in the bearings) explain why UFPs are to be expected. A discussion of oil seals used in gas turbine engines concludes that they will permit UFPs to cross them and enter the breathing air supply, in conjunction with a complex mixture of chemicals such triaryl phosphates which are neurotoxic. A consideration of the toxicology of Nano-particles concludes that their continual presence over a typical working lifetime of up to 20,000 hours in aircrew will predispose them to chronic respiratory problems and will exacerbate the translocation of neurotoxic substances across the blood brain barrier.en_UK
dc.language.isoenen_UK
dc.publisherGavin Publishersen_UK
dc.relationHoward CV, Johnson DW, Morton J, Michaelis S, Supplee D & Burdon J (2018) Is a Cumulative Exposure to a Background Aerosol of Nanoparticles Part of the Causal Mechanism of Aerotoxic Syndrome?. Nanomedicine and Nanoscience Research, pp. JNAN-139. https://www.gavinpublishers.com/article/view/is-a-cumulative-exposure-to-a-background-aerosol-of-nanoparticles-part-of-the-causal-mechanism-of-aerotoxic-syndromeen_UK
dc.rightsThis is an Open Access Journal Article Published Under Attribution-Share Alike CC BY-SA: Creative Commons Attribution-Share Alike 4.0 International License (https://creativecommons.org/licenses/by-sa/4.0/). With this license readers can share, distribute, download, even commercially, as long as the original source is properly cited.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by-sa/4.0/en_UK
dc.subjectAero Gas Turbine Enginesen_UK
dc.subjectAerotoxic Syndromeen_UK
dc.subjectAircraft Cabin Air Qualityen_UK
dc.subjectNano-Toxicologyen_UK
dc.subjectNeurological Diseaseen_UK
dc.subjectOil Sealsen_UK
dc.subjectParticulate Aerosolsen_UK
dc.subjectRespiratory Diseaseen_UK
dc.titleIs a Cumulative Exposure to a Background Aerosol of Nanoparticles Part of the Causal Mechanism of Aerotoxic Syndrome?en_UK
dc.typeJournal Articleen_UK
dc.citation.jtitleNanomedicine and Nanoscience Researchen_UK
dc.citation.issn2577-1477en_UK
dc.citation.spageJNANen_UK
dc.citation.epage139en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.identifier.urlhttps://www.gavinpublishers.com/article/view/is-a-cumulative-exposure-to-a-background-aerosol-of-nanoparticles-part-of-the-causal-mechanism-of-aerotoxic-syndromeen_UK
dc.citation.date07/02/2018en_UK
dc.contributor.affiliationUlster Universityen_UK
dc.contributor.affiliationUniversity of Daytonen_UK
dc.contributor.affiliationEuropean Sealing Associationen_UK
dc.contributor.affiliationHealth Sciences Stirlingen_UK
dc.contributor.affiliationInternational Association of Machinists & Aerospace Workersen_UK
dc.contributor.affiliationIndependenten_UK
dc.identifier.wtid1796864en_UK
dc.date.accepted2018-01-31en_UK
dcterms.dateAccepted2018-01-31en_UK
dc.date.filedepositdate2022-03-07en_UK
rioxxterms.apcnot chargeden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorHoward, C Vyvyan|en_UK
local.rioxx.authorJohnson, David W|en_UK
local.rioxx.authorMorton, John|en_UK
local.rioxx.authorMichaelis, Susan|en_UK
local.rioxx.authorSupplee, David|en_UK
local.rioxx.authorBurdon, Jonathan|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2022-03-07en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by-sa/4.0/|2022-03-07|en_UK
local.rioxx.filename1537165462new_article_pdf69025564.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source2577-1477en_UK
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