Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/34022
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles
Peer Review Status: Refereed
Title: Is a Cumulative Exposure to a Background Aerosol of Nanoparticles Part of the Causal Mechanism of Aerotoxic Syndrome?
Author(s): Howard, C Vyvyan
Johnson, David W
Morton, John
Michaelis, Susan
Supplee, David
Burdon, Jonathan
Keywords: Aero Gas Turbine Engines
Aerotoxic Syndrome
Aircraft Cabin Air Quality
Nano-Toxicology
Neurological Disease
Oil Seals
Particulate Aerosols
Respiratory Disease
Issue Date: Feb-2018
Date Deposited: 7-Mar-2022
Citation: Howard CV, Johnson DW, Morton J, Michaelis S, Supplee D & Burdon J (2018) Is a Cumulative Exposure to a Background Aerosol of Nanoparticles Part of the Causal Mechanism of Aerotoxic Syndrome?. Nanomedicine and Nanoscience Research, pp. JNAN-139. https://www.gavinpublishers.com/article/view/is-a-cumulative-exposure-to-a-background-aerosol-of-nanoparticles-part-of-the-causal-mechanism-of-aerotoxic-syndrome
Abstract: We present strong evidence for the presence of aerosols of Nano-particles (also termed Ultrafine Particles (UFPs) in aerosol science) in the breathing air of commercial aircraft using engine bleed air architecture. The physical and chemical nature of engine oils and the high temperatures attained in aircraft jet engines (up to 1700°C in the oil circulation and up to 30,000°C in the bearings) explain why UFPs are to be expected. A discussion of oil seals used in gas turbine engines concludes that they will permit UFPs to cross them and enter the breathing air supply, in conjunction with a complex mixture of chemicals such triaryl phosphates which are neurotoxic. A consideration of the toxicology of Nano-particles concludes that their continual presence over a typical working lifetime of up to 20,000 hours in aircrew will predispose them to chronic respiratory problems and will exacerbate the translocation of neurotoxic substances across the blood brain barrier.
URL: https://www.gavinpublishers.com/article/view/is-a-cumulative-exposure-to-a-background-aerosol-of-nanoparticles-part-of-the-causal-mechanism-of-aerotoxic-syndrome
Rights: This is an Open Access Journal Article Published Under Attribution-Share Alike CC BY-SA: Creative Commons Attribution-Share Alike 4.0 International License (https://creativecommons.org/licenses/by-sa/4.0/). With this license readers can share, distribute, download, even commercially, as long as the original source is properly cited.
Licence URL(s): http://creativecommons.org/licenses/by-sa/4.0/

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