Please use this identifier to cite or link to this item:
http://hdl.handle.net/1893/34022
Appears in Collections: | Faculty of Health Sciences and Sport Journal Articles |
Peer Review Status: | Refereed |
Title: | Is a Cumulative Exposure to a Background Aerosol of Nanoparticles Part of the Causal Mechanism of Aerotoxic Syndrome? |
Author(s): | Howard, C Vyvyan Johnson, David W Morton, John Michaelis, Susan Supplee, David Burdon, Jonathan |
Keywords: | Aero Gas Turbine Engines Aerotoxic Syndrome Aircraft Cabin Air Quality Nano-Toxicology Neurological Disease Oil Seals Particulate Aerosols Respiratory Disease |
Issue Date: | Feb-2018 |
Date Deposited: | 7-Mar-2022 |
Citation: | Howard CV, Johnson DW, Morton J, Michaelis S, Supplee D & Burdon J (2018) Is a Cumulative Exposure to a Background Aerosol of Nanoparticles Part of the Causal Mechanism of Aerotoxic Syndrome?. Nanomedicine and Nanoscience Research, pp. JNAN-139. https://www.gavinpublishers.com/article/view/is-a-cumulative-exposure-to-a-background-aerosol-of-nanoparticles-part-of-the-causal-mechanism-of-aerotoxic-syndrome |
Abstract: | We present strong evidence for the presence of aerosols of Nano-particles (also termed Ultrafine Particles (UFPs) in aerosol science) in the breathing air of commercial aircraft using engine bleed air architecture. The physical and chemical nature of engine oils and the high temperatures attained in aircraft jet engines (up to 1700°C in the oil circulation and up to 30,000°C in the bearings) explain why UFPs are to be expected. A discussion of oil seals used in gas turbine engines concludes that they will permit UFPs to cross them and enter the breathing air supply, in conjunction with a complex mixture of chemicals such triaryl phosphates which are neurotoxic. A consideration of the toxicology of Nano-particles concludes that their continual presence over a typical working lifetime of up to 20,000 hours in aircrew will predispose them to chronic respiratory problems and will exacerbate the translocation of neurotoxic substances across the blood brain barrier. |
URL: | https://www.gavinpublishers.com/article/view/is-a-cumulative-exposure-to-a-background-aerosol-of-nanoparticles-part-of-the-causal-mechanism-of-aerotoxic-syndrome |
Rights: | This is an Open Access Journal Article Published Under Attribution-Share Alike CC BY-SA: Creative Commons Attribution-Share Alike 4.0 International License (https://creativecommons.org/licenses/by-sa/4.0/). With this license readers can share, distribute, download, even commercially, as long as the original source is properly cited. |
Licence URL(s): | http://creativecommons.org/licenses/by-sa/4.0/ |
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